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A ventricle is one of two large chambers located toward the bottom of the that collect and expel towards the peripheral beds within the body and lungs. The blood by a ventricle is supplied by an atrium, an adjacent chamber in the upper heart that is smaller than a ventricle. Interventricular means between the ventricles (for example the interventricular septum), while intraventricular means within one ventricle (for example an intraventricular block).

In a four-chambered heart, such as that in , there are two ventricles that operate in a double circulatory system: the right ventricle pumps blood into the pulmonary circulation to the , and the left ventricle pumps blood into the systemic circulation through the .


Structure
Ventricles have thicker walls than atria and generate higher . The physiological load on the ventricles requiring pumping of blood throughout the body and lungs is much greater than the pressure generated by the atria to fill the ventricles. Further, the left ventricle has thicker walls than the right because it needs to pump blood to most of the body while the right ventricle fills only the lungs.

On the inner walls of the ventricles are irregular muscular columns called trabeculae carneae which cover all of the inner ventricular surfaces except that of the , in the right ventricle. There are three types of these muscles. The third type, the , give origin at their apices to the which attach to the cusps of the and to the .

The mass of the left ventricle, as estimated by magnetic resonance imaging, averages 143 g ± 38.4 g, with a range of 87–224 g.

The right ventricle is equal in size to the left ventricle and contains roughly 85 millilitres (3 imp fl oz; 3 US fl oz) in the adult. Its upper front surface is circled and convex, and forms much of the surface of the heart. Its under surface is flattened, forming part of the diaphragmatic surface of the heart that rests upon the diaphragm.

Its posterior wall is formed by the ventricular septum, which bulges into the right ventricle, so that a transverse section of the cavity presents a semilunar outline. Its upper and left angle forms a conical pouch, the , from which the pulmonary artery arises. A tendinous band, called the tendon of the conus arteriosus, extends upward from the right atrioventricular fibrous ring and connects the posterior surface of the conus arteriosus to the aorta.


Shape
The left ventricle is longer and more conical in shape than the right, and on transverse section its concavity presents an oval or nearly circular outline. It forms a small part of the sternocostal surface and a considerable part of the diaphragmatic surface of the heart; it also forms the apex of the heart. The left ventricle is thicker and more muscular than the right ventricle because it pumps blood at a higher pressure.

The right ventricle is triangular in shape and extends from the tricuspid valve in the right atrium to near the apex of the heart. Its wall is thickest at the apex and thins towards its base at the atrium. When viewed via cross section however, the right ventricle seems to be crescent shaped.Leng J. Right ventricle. In: Weyman AE, ed. Principle andpractice of echocardiography. Philadelphia: Lippincott Williams& Wilkins, 1994:901–21Haddad F, Couture P, Tousignant C, Denault AY. The right ventricle in cardiac surgery, a perioperative perspective: I. Anatomy, physiology, and assessment. Anesth Analg. 2009;108(2):407-21. doi:10.1213/ane.0b013e31818f8623. The right ventricle is made of two components: the sinus and the conus. The Sinus is the inflow which flows away from the tricuspid valve. Haddad F, Couture P, Tousignant C, Denault AY. The right ventricle in cardiac surgery, a perioperative perspective: I. Anatomy, physiology, and assessment. Anesth Analg. 2009;108(2):407-21. doi:10.1213/ane.0b013e31818f8623. Three bands made from muscle, separate the right ventricle: the parietal, the septal, and the moderator band. The moderator band connects from the base of the anterior papillary muscle to the ventricular septum.Farb A, Burke AP, Virmani R. Anatomy and pathology of theright ventricle (including acquired tricuspid and pulmonicvalve disease). Cardiol Clin 1992;10:1–21


Development
By young adulthood, the walls of the left ventricle have thickened from three to six times greater than that of the right ventricle. This reflects the typical five times greater pressure workload this chamber performs while accepting blood returning from the pulmonary veins at ~80mmHg pressure (equivalent to around 11 kPa) and pushing it forward to the typical ~120mmHg pressure (around 16.3 kPa) in the aorta during each heartbeat. (The pressures stated are resting values and stated as relative to surrounding atmospheric which is the typical "0" reference pressure used in medicine.)


Function
During systole, the ventricles contract, pumping blood through the body. During , the ventricles relax and fill with blood again.

The left ventricle receives oxygenated blood from the via the and pumps it through the via the , into the systemic circulation. The left ventricular muscle must relax and contract quickly and be able to increase or lower its pumping capacity under the control of the nervous system. In the diastolic phase, it has to relax very quickly after each contraction so as to quickly fill with the oxygenated blood flowing from the . Likewise in the systolic phase, the left ventricle must contract rapidly and forcibly to pump this blood into the aorta, overcoming the much higher aortic pressure. The extra pressure exerted is also needed to stretch the aorta and other arteries to accommodate the increase in blood volume.

The right ventricle receives deoxygenated blood from the right atrium via the and pumps it into the pulmonary artery via the , into the pulmonary circulation.


Pumping volume
The typical healthy adult heart pumping volume is ~5 liters/min, resting. Maximum capacity pumping volume extends from ~25 liters/min for non-athletes to as high as ~45 liters/min for Olympic level athletes.


Volumes
In , the performance of the ventricles are measured with several volumetric parameters, including end-diastolic volume (EDV), end-systolic volume (ESV), (SV) and ejection fraction (Ef).


Pressures
Ventricular pressure is a measure of within the ventricles of the .


Left
During most of the , ventricular pressure is less than the pressure in the , but during systole, the ventricular pressure rapidly increases, and the two pressures become equal to each other (represented by the junction of the blue and red lines on the diagram on this page), the opens, and blood is pumped to the body.

Elevated left ventricular end-diastolic pressure has been described as a risk factor in cardiac surgery.

Noninvasive approximations have been described.

An elevated pressure difference between the and the left ventricular pressure may be indicative of .


Right
Right ventricular pressure demonstrates a different pressure-volume loop than left ventricular pressure.


Dimensions
The heart and its performance are also commonly measured in terms of dimensions, which in this case means distances, usually measured in millimeters. This is not as informative as volumes but may be much easier to estimate with (e.g., M-Mode echocardiography or with , which is mostly used for animal model research). Optimally, it is specified with which plane the distance is measured in, e.g. the dimension of the longitudinal plane.

Left ventricular end-diastolic dimension
| LVEDD or sometimes LVDD || The end-diastolic dimension of the left ventricle. | 48 mm,
Range 36 – 56 mm
Right ventricular end-diastolic dimension
| RVEDD or sometimes RVDD || The end-diastolic dimension of the right ventricle. | Range 10 – 26 mmPage 41 in:
(2025). 9780729539111, Churchill Livingstone.
Left ventricular end-systolic dimension
| LVESD or sometimes LVSD || The end-systolic dimension of the left ventricle. | Range 20 – 40 mm
Right ventricular end-systolic dimension
| RVESD or sometimes RVSD || The end-systolic dimension of the right ventricle. | Range 10 – 26 mm
8.3 mm,
Range 7 – 11 mm
8.3 mm,
Range 7 – 11 mm
Women: 4 - 8 mm
Men: 5 - 9 mm
4 - 7 mm
16  mm
Range 24 – 40 mm

Fractional shortening ( FS) is the fraction of any diastolic dimension that is lost in systole. When referring to endocardial luminal distances, it is EDD minus ESD divided by EDD (times 100 when measured in percentage). Retrieved on April 7, 2010 Normal values may differ somewhat dependent on which is used to measure the distances. Normal range is 25–45%, Mild is 20–25%, Moderate is 15–20%, and Severe is <15%. Cardiology Diagnostic Tests Midwall fractional shortening may also be used to measure diastolic/systolic changes for inter-ventricular septal dimensions and posterior wall dimensions. However, both endocardial and midwall fractional shortening are dependent on myocardial wall thickness, and thereby dependent on long-axis function.

By comparison, a measure of short-axis function termed epicardial volume change (EVC) is independent of myocardial wall thickness and represents isolated short-axis function.


Clinical significance
An is an irregular heartbeat that can occur in the ventricles or atria. Normally the heartbeat is initiated in the of the atrium but initiation can also occur in the of the ventricles, giving rise to premature ventricular contractions, also called ventricular extra beats. When these beats become grouped the condition is known as ventricular tachycardia.

Another form of arrhythmia is that of the ventricular escape beat. This can happen as a compensatory mechanism when there is a problem in the conduction system from the SA node.

The most severe form of arrhythmia is ventricular fibrillation which is the most common cause of and subsequent sudden death.

  • Ventricular septal defect
  • Atrioventricular septal defect


See also


External links

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